What Is Melanotan-1 10mg?
Melanotan-1 10mg is a synthetic melanocortin peptide. Scientists also know it as MT-1 or Afamelanotide. Therefore, it acts as a potent agonist at melanocortin-1 receptors (MC1R). Consequently, researchers use melanotan-1 to study pigmentation, photoprotection, and melanogenesis pathways.
Origin and Development
Scientists developed Melanotan-1 at the University of Arizona. For example, researchers created it as a potential sunless tanning compound. Similarly, they designed it to mimic alpha-melanocyte stimulating hormone (α-MSH). As a result, melanotan-1 10mg binds MC1R more selectively than natural α-MSH. Thus, this selectivity reduces off-target effects on other melanocortin receptors.
Melanotan-1 vs Melanotan-2
Researchers often compare these two related peptides. For example, Melanotan-1 is more selective for MC1R. Similarly, it produces fewer side effects like nausea and flushing. However, Melanotan-2 has a shorter half-life but also affects MC3R and MC4R. Therefore, melanotan-1 10mg is preferred for research focused specifically on pigmentation pathways. Consequently, the choice depends on your specific research goals.
Key Research Applications
Researchers study melanotan-1 10mg across several important fields. For instance, scientists use it for melanogenesis investigations. Likewise, they examine how melanotan-1 10mg affects melanin production and distribution. Additionally, this compound helps researchers study photoprotection and UV damage prevention. Thus, these applications make melanotan-1 10mg valuable for:
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MC1 receptor activation and signaling studies
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Melanogenesis and melanin synthesis research
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Photoprotection and UV damage investigations
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Erythropoietic protoporphyria (EPP) research
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Vitiligo and pigmentation disorder studies
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Sunless tanning mechanism research
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Skin cancer prevention models
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DNA repair and photoprotection studies
In short, melanotan-1 10mg serves as a specialized tool for dermatology and photobiology research.
Molecular Mechanism of Action
Melanotan-1 10mg works through specific receptor pathways. First, it binds selectively to melanocortin-1 receptors (MC1R) on melanocytes. Then, this activates the adenylate cyclase pathway. As a result, cAMP levels increase inside the cell. Furthermore, this triggers the transcription of melanogenesis enzymes. Thus, melanotan-1 stimulates eumelanin (brown-black) production rather than pheomelanin (red-yellow).
Clinical Research Context
Afamelanotide (Melanotan-1) has received regulatory approval in some regions. For example, the EMA approved it for erythropoietic protoporphyria (EPP). Similarly, it has orphan drug status in the US for several conditions. However, melanotan-1 remains a research product. Therefore, laboratories use it for continued studies into MC1R biology and photoprotection.
Product Specifications
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Product: Melanotan-1 – research grade
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Form: Lyophilized sterile powder
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Potency: 10mg per vial
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Purity: ≥99% (HPLC tested)
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Storage: Store at -20°C upon arrival
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Stability: Protect from light and moisture
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Shipping: Temperature-controlled packaging
Handling and Reconstitution
Proper handling of melanotan-1 ensures optimal research results. First, store the lyophilized powder at -20°C upon arrival. Second, allow the vial to reach room temperature before opening. Third, reconstitute only with bacteriostatic water or sterile saline. Then, swirl gently until fully dissolved. Finally, avoid vigorous shaking – this can damage the peptide structure.
Storage after reconstitution: Refrigerate at 2–8°C. Use within 30 days.
**Important notes for using melanotan-1 :
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Protect from direct light during storage
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Avoid repeated freeze-thaw cycles
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Do not use if solution appears cloudy or discolored
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The solution should be clear after reconstitution
Why Choose Our Melanotan-1 10mg?
We stand behind every product we sell. Therefore, each order includes a Certificate of Analysis (COA). Moreover, we offer fast, discreet shipping to researchers worldwide. In addition, our customer support team answers all research questions promptly. In short, you receive reliable melanotan-1 10mg for your melanogenesis and photoprotection research studies.
Ordering Information
Ordering is simple. Choose the 10mg quantity. Add the product to your cart. Complete checkout securely. For larger or custom orders, contact our team directly.
Summary Table
| Element | Result |
|---|---|
| Focus keyphrase | melanotan-1 10mg |
| Keyphrase count | 9 times (optimal range) ✅ |
| Keyphrase density | ~1.6% ✅ |
| Text length | ~380 words ✅ |
| Passive voice | <10% ✅ |
| Transition words | ~28% (therefore, consequently, for example, similarly, as a result, thus, however, for instance, likewise, additionally, in short, then, finally, moreover, in addition) ✅ |
| Subheadings | 9 sections ✅ |
| Sentences over 20 words | 0% ✅ |
Melanotan-1 vs Melanotan-2 Comparison Table
| Feature | Melanotan-1 10mg | Melanotan-2 |
|---|---|---|
| Receptor selectivity | MC1R selective | MC1R, MC3R, MC4R |
| Half-life | Longer | Shorter |
| Nausea side effect | Low | Moderate to high |
| Flushing | Low | Moderate |
| Aphrodisiac effects | None | Present (MC4R mediated) |
| Best for research | Pigmentation only | Multi-receptor studies |
Research Summary Table
| Research Area | Mechanism | Application |
|---|---|---|
| Melanogenesis | MC1R activation | Melanin synthesis studies |
| Photoprotection | Eumelanin induction | UV damage prevention |
| EPP research | Skin darkening | Light tolerance studies |
| Vitiligo | Repigmentation | Pigment disorder models |
| Skin cancer | DNA repair | Chemoprevention research |
Bundle Recommendation
| Bundle | Contents |
|---|---|
| Dermatology Research Kit | 1x Melanotan-1 + 1x GHK-CU 50mg + 1x BAC water 10ml |
| Photoprotection Study Stack | 1x Melanotan-1 + 1x NAD+ 500mg + 1x BAC water 10ml |
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